Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Study Inquiry 415-654-5281
clinicaltrials@vir.bio


Study Location:

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English | Cymraeg
Be Part of Research - Trial Details - Safety, Pharmacokinetics, and Preliminary Efficacy of AMX-500 in Metastatic Castration Resistant Prostate Cancer (mCRPC)

Safety, Pharmacokinetics, and Preliminary Efficacy of AMX-500 in Metastatic Castration Resistant Prostate Cancer (mCRPC)

Recruiting

Open to: MALE

Age: 18.0 - N/A

Medical Conditions

Prostatic Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The study will be conducted in 4 parts and will commence with dose escalation of AMX-500 as a monotherapy (Part 1), followed by monotherapy dose expansion (Part 2).

* Part 1 (Monotherapy Dose Escalation): Single-agent AMX-500 dose escalation * Part 2 (Monotherapy Dose Expansion): Single-agent AMX-500 dose expansion

The study may subsequently continue via a protocol amendment with dose escalation of AMX-500 combinations (Part 3) followed by combination therapy dose expansion (Part 4).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Aug 2023 Sep 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Pharmaceutical form: Solution for infusion Route of administration: Intravenous (IV) infusion

Intervention Arm Group : Part 1: AMX-500 Monotherapy Dose Escalation;Part 2: AMX-500 Monotherapy Dose Expansion;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Investigational Site Number: 300
    London
    SM2 5PT


The study is sponsored by Vir Biotechnology, Inc.





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Read full details for Trial ID: NCT05997615
Last updated 14 July 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.