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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Sui Hsien
Wong
sui.wong@gstt.nhs.uk
isabelle
chow
Isabelle.chow@gstt.nhs.uk
More information about this study, what is involved and how to take part can be found on the study website.
Visual disturbances and blindness
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Visual Snow Syndrome (VSS) is a neurological condition where affected people see flickering dots across their whole visual field, & may have other symptoms such as light sensitivity, after-images, trailing of images, & tinnitus. Functional Magnetic Resonance Imaging (fMRI) studies in VSS have shown brain network dysregulation involving the visual pathway. There is currently no evidence-based validated treatment for VSS, therefore the current standard of care is no treatment.
This research trial is to test the treatment of an intensive mindfulness programme, using the Mindfulness Based Cognitive Therapy customised for visual symptoms (MBCT-vision) programme, for people with Visual Snow Syndrome. MBCT-vision is a group learning programme, where people meet once weekly for 8 weeks. During these once weekly sessions, they learn mindfulness practices. The group discussions about the mindfulness practices introduces cognitive behavioural skills. Participants are given daily home practices between these weekly group learning sessions. We completed a study (IRAS 266101) showing MBCT-vision was a feasible treatment for VSS.
This clinical trial is a 'randomised controlled trial'(RCT), where the effectiveness of a treatment is evaluated by comparison between two groups. We are recruiting people with VSS. Participants will be randomly allocated to one of two groups: one group receives MBCT-vision; while another group received standard care only for 5 months. The second group is called a waiting-list control group, whereby after 5 months, they will receive MBCT-vision treatment. The study will be conducted from single centre at a tertiary care hospital and the MBCT-vision is delivered online.
The key outcome of interest is severity of Visual Snow Syndrome on a 0-10 visual analogue scale. Other outcome measures will be collected to understand the effect of MBCT-vision, including quality of life and psychological wellbeing.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Interventional type: Education or Self-Management;Psychological & Behavioural;
You can take part if:
You may not be able to take part if:
o People with co-morbid conditions affecting vision o Patient with a current severe depressive or psychotic episode o Patient with severe difficulties in emotional regulation o Patient unable to provide informed consent for participation o Patient with insufficient understanding of spoken English (due to need to participate in group discussions) o Patients who have previously completed MBCT or similar mindfulness interventions Metabolomics sub-study: healthy controls exclusion criteria: o Person unable to provide informed consent o Person with other co-morbid medical or psychological conditions o Person aged < 16 or > 80years
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
isabelle
chow
Isabelle.chow@gstt.nhs.uk
Dr
Sui Hsien
Wong
sui.wong@gstt.nhs.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST and funded by Visual Snow Initiative .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 58464
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