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Be Part of Research - Trial Details - A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

Not Recruiting

Open to: MALE

Age: 18.0 - N/A

Medical Conditions

Prostatic Neoplasms
Hypersensitivity


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to assess the real-world outcomes differences between apalutamide or enzalutamide plus androgen deprivation therapy (ADT) for the treatment of participants with metastatic hormone-sensitive prostate cancer (mHSPC).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2023 Jun 2026

OBSERVATIONAL

Intervention Type : DRUG
Intervention Description : No interventions will be administered as a part of this study. Participants will receive apalutamide as per their routine clinical practice.

Intervention Arm Group : Apalutamide Plus Androgen Deprivation Therapy (ADT);

Intervention Type : DRUG
Intervention Description : No interventions will be administered as a part of this study. Participants will receive enzalutamide as per their routine clinical practice.

Intervention Arm Group : Enzalutamide Plus Androgen Deprivation Therapy (ADT);



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Dorset County Hospital Nhs Foundation Trust
    Dorchester
    DT1 2JY
  • Scunthorpe General Hospital
    Scunthorpe
    DN15 7BH
  • Royal Surrey County Hospital NHS Trust
    Guildford
    GU2 7XX
  • Taunton and Somerset NHS Foundation Trust
    Taunton
    TA1 5DA
  • Torbay Hospital-Devon
    Devon
    TQ2 7AA
  • Pennine Care Nhs Foundation Trust
    Oldham
    OL1 2JH
  • Frimley Health NHS Foundation Trust
    Berkshire
    SL2 4HL
  • University Hospitals Sussex NHS Foundation Trust Worthing Hospital
    Worthing
    BN11 2DH
  • Royal Cornwall Hospitals NHS Trust - Royal Cornwall Hospital
    Cornwall
    TR1 3LJ
  • University College London Hospitals Nhs Foundation Trust
    London
    NW1 2PG
  • Royal Free London NHS Foundation Trust
    London
    NW3 2QG


The study is sponsored by Janssen-Cilag Ltd.





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Read full details for Trial ID: NCT05901649
Last updated 18 July 2025

This page is to help you find out about a research study and if you may be able to take part

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