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Be Part of Research - Trial Details - Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD

Not Recruiting

Open to: ALL

Age: 35.0 - 80.0

Medical Conditions

Parkinson Disease


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical meaningful motor progression over 78 weeks in subjects with Parkinson's disease who have a pathogenic variant in the glucocerebrosidase 1 (GBA1) gene (GBA-PD).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Mar 2023 Mar 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : BIA 28-6156 10 mg, once daily, oral administration.

Intervention Arm Group : BIA 28-6156 10 mg;

Intervention Type : DRUG
Intervention Description : BIA 28-6156 60 mg, once daily, oral administration.

Intervention Arm Group : BIA 28-6156 60 mg;

Intervention Type : DRUG
Intervention Description : Placebo, once daily, oral administration.

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University Hospitals Plymouth NHS Trust
    Plymouth
  • Glasgow Memory Clinic
    Glasgow
  • The Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital
    Newcastle Upon Tyne
  • King's College London - David Goldberg Centre
    London
  • NHS Tayside-Ninewells Hospital and Medical School
    Dundee


The study is sponsored by Bial R&D Investments, S.A.





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Read full details for Trial ID: NCT05819359
Last updated 20 August 2024

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