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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Jonathan Badrock 02076704602
mrcctu.refine@ucl.ac.uk


Study Location:

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Be Part of Research - Trial Details - REduced Frequency ImmuNE Checkpoint Inhibition in Cancers

REduced Frequency ImmuNE Checkpoint Inhibition in Cancers

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Carcinoma, Renal Cell


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The REFINE trial aims to asses whether giving an immunotherapy drug less-often to patients with advanced cancer, results in fewer side effects whilst continuing to be an effective treatment. The question will be assessed in different tumour types by means of different cohorts within an overarching trial protocol.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

May 2022 Apr 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : 60-minute IV infusion, as a flat dose of 480mg

Intervention Arm Group : Extended interval;Standard interval;

Intervention Type : DRUG
Intervention Description : 60-minute IV infusion, as a flat dose of 400mg

Intervention Arm Group : Extended interval;Standard interval;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Castle Hill Hospital
    Hull
    HU16 5JQ
  • The Christie
    Manchester
  • Addenbrooke's Hospital
    Cambridge
    Cambridgeshire


The study is sponsored by University College, London and is in collaboration with JP Moulton Charitable Foundation.




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Read full details for Trial ID: NCT04913025
Last updated 16 September 2022

This page is to help you find out about a research study and if you may be able to take part

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