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Contact Information:

Joris Wilms +4570261414
clinicaltrials@ymabs.com


Study Location:

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Be Part of Research - Trial Details - Naxitamab for High-Risk Neuroblastoma Patients with Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone And/or Bone Marrow

Naxitamab for High-Risk Neuroblastoma Patients with Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone And/or Bone Marrow

Recruiting

Open to: ALL

Age: 1.0 - N/A

Medical Conditions

Neuroblastoma


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Children and adults diagnosed with high-risk neuroblastoma patients with primary refractory disease or incomplete response to salvage treatment in bone and/or bone marrow will be treated for up to 101 weeks with naxitamab and granulocyte-macrophage colony stimulating factor (GM-CSF). Patients will be followed for up to five years after first dose.

Naxitamab, also known as hu3F8 is a humanised monoclonal antibody targeting GD2

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Apr 2018 Apr 2026

INTERVENTIONAL

Intervention Type : BIOLOGICAL
Intervention Description : Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Humanized IgG1 monoclonal GD2 antibody

Intervention Arm Group : GM-CSF + Naxitamab;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Leeds General Infirmary
    Leeds
    LS1 3EX
  • University Hospital Southampton
    Southampton
    SO16 6YD
  • The Royal Marsden
    London
    SW3 6JJ
  • The Royal Glasgow Children's Hospital
    Glasgow
    G51 4TF


The study is sponsored by Y-mAbs Therapeutics




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Read full details for Trial ID: NCT03363373
Last updated 18 February 2025

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