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A Study to Evaluate the Efficacy and Safety of TEV-48125 (Fremanezumab) for the Prevention of Episodic Cluster Headache (ECH)


Open to: All Genders

Age: 18 Years - 70 Years

Medical Conditions

Episodic Cluster Headache

This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.

This is a 13-week, multicenter, randomized, double-blind, double-dummy, placebo-controlled, parallel-group study to compare the efficacy and safety of 2 dose regimens of TEV-48125 (Fremanezumab) versus placebo in adult participants for the prevention of ECH.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jan 2017 May 2019


Intervention Type : Drug
Intervention Description : Fremanezumab will be administered per dose and schedule specified in the arm.

Intervention Arm Group : Fremanezumab 675 mg/Placebo/Placebo;Fremanezumab 900/225/225 mg

Intervention Type : Drug
Intervention Description : Placebo matching to fremanezumab will be administered per schedule specified in the arm.

Intervention Arm Group : Placebo

You can take part if:

You may not be able to take part if:

This is in the inclusion criteria above

Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Teva Investigational Site 34224
    G51 4TF
  • Teva Investigational Site 34222
    L9 7LJ
  • Teva Investigational Site 34223
    SE1 9RT
  • Teva Investigational Site 34220
    W6 8RF
  • Teva Investigational Site 34221
    OX3 9DU

The study is sponsored by Teva Branded Pharmaceutical Products R&D, Inc.

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for Trial ID: NCT02945046

Last updated 06 November 2021

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