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Be Part of Research - Trial Details - QUantum Genomics Incremental Dosing in Heart Failure - QUID-HF

QUantum Genomics Incremental Dosing in Heart Failure - QUID-HF

Stopped

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Heart Failure


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Heart Failure (HF) a common clinical condition characterized by either by a heart that does not pump sufficiently or becomes stiff. A variety of mechanisms contribute to progressive cardiac remodeling and dysfunction.

A new therapeutic approaches by preventing activation of the brain neuromodulatory pathway, may lead to improve HF.

QCG001 is a prodrug of EC33, a aminopeptidase A (APA) inhibitor. QCG001 has been shown to be an antihypertensive agent in animal models.

This study investigates the safety and efficacy of QGC001 in HF patients.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2016 Sep 2018

INTERVENTIONAL

Intervention Type : DRUG
Intervention Arm Group : QGC001;

Intervention Type : DRUG
Intervention Description : Lactose capsule manufactured to mimic QGC001 50 mg and 250 mg

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Ninewells Hospital
    Dundee
    DD1 9SY
  • University of Birmingham Institute of Cardiovascular Sciences City Hospital,
    Birmingham
    England
    B18 7QH


The study is sponsored by Quantum Genomics SA




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Read full details for Trial ID: NCT02780180
Last updated 11 October 2018

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