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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Theravance Biopharma 1-855-633-8479
medinfo@theravance.com


Study Location:

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Be Part of Research - Trial Details - Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic NOH in Participants with Multiple System Atrophy

Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic NOH in Participants with Multiple System Atrophy

Recruiting

Open to: ALL

Age: 30.0 - N/A

Medical Conditions

Multiple System Atrophy
Shy-Drager Syndrome
Hypotension, Orthostatic
Hypotension
Atrophy


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This is a Phase 3, multi-center, randomized withdrawal study to evaluate the efficacy and durability of ampreloxetine in participants with MSA and symptomatic nOH after 20 weeks of treatment. This study includes 4 periods: Screening, open label, randomized withdrawal, and long-term treatment extension (LTE).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2023 Dec 2024

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Oral tablet, QD

Intervention Arm Group : Ampreloxetine (Open Label);Ampreloxetine (Randomized Withdrawal);Long-Term Extension Period;

Intervention Type : DRUG
Intervention Description : Oral tablet, QD

Intervention Arm Group : Ampreloxetine (Randomized Withdrawal);



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Salford Royal Hospital
    Salford
    M6 8HD
  • Barts Health
    London
    EC1M 6BQ
  • Autonomic Unit, National Hospital for Neurology & Neurosurgery
    London
    WC1N 3BG
  • University Hospitals Birmingham NHS Foundation Trust
    Birmingham
    B15 2GW

Theravance Biopharma 1-855-633-8479
medinfo@theravance.com



The study is sponsored by Theravance Biopharma




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Read full details for Trial ID: NCT05696717
Last updated 17 December 2024

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