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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Reference Study ID Number: GO42286 https://forpatients.roche.com/ 888-662-6728
global-roche-genentech-trials@gene.com


Study Location:

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Be Part of Research - Trial Details - A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

Recruiting

Open to: ALL

Age: N/A - 17.0

Medical Conditions

Central Nervous System Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study will evaluate the safety, pharmacokinetics, and efficacy of alectinib in children and adolescents with ALK fusion-positive solid or CNS tumors for whom prior treatment has proven to be ineffective or for whom there is no satisfactory standard treatment available.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2021 Feb 2028

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Participants will receive twice-daily alectinib capsules on Days 1-28 of each 28-day cycle

Intervention Arm Group : ALK-Fusion Positive;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Great Ormond Street Hospital
    London
    WC1N 3JH
  • Royal Manchester Childrens Hospital
    Manchester
    M13 9WL
  • Royal Marsden Hospital (Sutton)
    Sutton
    SM2 5PT
  • Great North Children's Hospital
    Newcastle upon Tyne
    NE1 4LP

Reference Study ID Number: GO42286 https://forpatients.roche.com/ 888-662-6728
global-roche-genentech-trials@gene.com



The study is sponsored by Hoffmann-La Roche




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Read full details for Trial ID: NCT04774718
Last updated 03 June 2025

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