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Be Part of Research - Trial Details - A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight

A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight

Not Recruiting

Open to: ALL

Age: 6.0 - 18.0

Medical Conditions

Obesity


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study will look at how well semaglutide helps children and teenagers losing weight. This will be tested by comparing the effect on body weight in children and teenagers taking semaglutide in comparison to placebo, a "dummy" medicine. In addition to taking the medicine, the child's parent and the child will have talks with study staff about healthy food choices, how to be more physically active and what your child can do to try to lose weight. The child will either get semaglutide or a "dummy" medicine. Which treatment the child will get is decided by chance. Semaglutide is an approved medicine for type 2 diabetes and weight management in adults.

The child will get one injection once a week. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. The study will last for about 2 ½ years (132 weeks).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2023 Sep 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Semaglutide will be administered subcutaneously once weekly.

Intervention Arm Group : Group Kids;Group Teens;

Intervention Type : DRUG
Intervention Description : Placebo will be administered subcutaneously once-weekly.

Intervention Arm Group : Group Kids;Group Teens;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Birmingham Children's Hospital
    Birmingham
    B4 6NH
  • Alder Hey Children's Hospital
    Liverpool
    L12 2AP
  • Leeds Children's Hospital
    Leeds
    LS1 3EX
  • University Hospitals Bristol & Weston NHS Foundation Trust
    Bristol
    BS2 8BJ


The study is sponsored by Novo Nordisk A/S




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Read full details for Trial ID: NCT05726227
Last updated 28 January 2025

This page is to help you find out about a research study and if you may be able to take part

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