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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com 855-907-3286
Clinical.Trials@bms.com


First line of the email MUST contain the NCT# and Site #.


Study Location:

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English | Cymraeg
Be Part of Research - Trial Details - A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Multiple Myeloma
Neoplasms, Plasma Cell


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to compare the efficacy and safety of mezigdomide (CC-92480), bortezomib and dexamethasone (MeziVd) versus pomalidomide, bortezomib and dexamethasone (PVd) in participants with relapsed or refractory multiple myeloma (RRMM) who received between 1 to 3 prior lines of therapy and who have had prior lenalidomide exposure.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2022 Nov 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Specified dose on specified days

Intervention Arm Group : MeziVd (mezigdomide, bortezomib and dexamethasone);

Intervention Type : DRUG
Intervention Description : Specified dose on specified days

Intervention Arm Group : PVd (pomalidomide, bortezomib and dexamethasone);

Intervention Type : DRUG
Intervention Description : Specified dose on specified days

Intervention Arm Group : MeziVd (mezigdomide, bortezomib and dexamethasone);PVd (pomalidomide, bortezomib and dexamethasone);

Intervention Type : DRUG
Intervention Description : Specified dose on specified days

Intervention Arm Group : MeziVd (mezigdomide, bortezomib and dexamethasone);PVd (pomalidomide, bortezomib and dexamethasone);



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Barnet Hospital
    Barnet
    EN5 3DJ
  • Addenbrooke's Hospital
    Cambridge
    Cambridgeshire
    CB2 0QQ
  • Leicester Royal Infirmary
    Leicester
    Leicestershire
    LE1 5WW
  • Hammersmith Hospital
    London
    London, City of
    W12 0HS
  • King's College Hospital
    London
    Greater London
    SE5 9RS
  • The Royal Cornwall Hospital
    Truro
    England
    TR1 3LJ
  • Lanarkshire NHS Trust - Monklands Hospital
    Airdrie
    Great Britain
    ML6 OJS
  • Freeman Hospital
    Newcastle upon Tyne
    NE7 7DN
  • Royal Stoke University Hospital
    Stoke-on-Trent
    ST4 6QG

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com 855-907-3286
Clinical.Trials@bms.com


First line of the email MUST contain the NCT# and Site #.



The study is sponsored by Celgene




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Read full details for Trial ID: NCT05519085
Last updated 29 April 2025

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