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Contact Information:

Moderna Clinical Trials Support Center
1-877-777-7187
clinicaltrials@modernatx.com


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Be Part of Research - Trial Details - Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

Recruiting

Open to: All Genders

Age: 18 Years - N/A

Medical Conditions

Advanced Solid Tumors


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


The primary goal of this study is to assess the safety and tolerability of mRNA-4359 administered alone and in combination with pembrolizumab.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Aug 2022 Dec 2027

Interventional

Intervention Type : Biological
Intervention Description : Intramuscular Injection

Intervention Arm Group : Arm 1a (Dose Escalation): mRNA-4359 Alone;Arm 1b (Dose Confirmation): mRNA-4359 in Combination with Pembrolizumab;Arm 2 (Dose Expansion): mRNA-4359 in Combination with Pembrolizumab

Intervention Type : Biological
Intervention Description : Intravenous infusion

Intervention Arm Group : Arm 1b (Dose Confirmation): mRNA-4359 in Combination with Pembrolizumab;Arm 2 (Dose Expansion): mRNA-4359 in Combination with Pembrolizumab



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University Hospital Southampton NHS Foundation Trust
    Southampton
    SO16 6YD
  • Churchill Hospital
    Oxford
    Ox3 7LE
  • University College London Hospitals NHS Foundation Trust
    London
    NW1 2PG
  • Beatson West of Scotland Cancer Centre
    Glasgow
    Scotland
    G12 0YN
  • Imperial College London
    London
    W12 0HS
  • Queen Elizabeth Hospital Birmingham
    Birmingham
    B15 2GW
  • Guy's and St. Thomas' NHS Foundation Trust
    London
    SE1 7EH

Moderna Clinical Trials Support Center
1-877-777-7187
clinicaltrials@modernatx.com



The study is sponsored by ModernaTX, Inc.




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Read full details for Trial ID: NCT05533697
Last updated 25 April 2024

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