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Be Part of Research - Trial Details - Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

Completed

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Urinary Bladder Neoplasms
Urethral Neoplasms
Carcinoma, Transitional Cell
Kidney Neoplasms
Ureteral Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective for urinary tract cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin plus gemcitabine with or without paclitaxel in treating patients who have stage IV urinary tract cancer.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

May 2001 Jun 2004

Publications

"Bellmunt J, von der Maase H, Mead GM, et al.: Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine (PCG) and gemcitabine/cisplatin (GC) in patients with locally advanced (LA) or metastatic (M) urothelial cancer without prior systemic therapy: EORTC30987/Intergroup study. [Abstract] J Clin Oncol 25 (Suppl 18): A-LBA5030, 242s, 2007."; null

INTERVENTIONAL

Intervention Type : DRUG

Intervention Type : DRUG

Intervention Type : DRUG



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Saint Bartholomew's Hospital
    London
    England
    EC1A 7BE
  • Royal South Hants Hospital
    Southampton
    England
    SO14 0YG
  • Northern Centre for Cancer Treatment at Newcastle General Hospital
    Newcastle Upon Tyne
    England
    NE4 6BE
  • Velindre Cancer Center at Velinde Hospital
    Cardiff
    Wales
    CF14 2TL
  • St. James's University Hospital
    Leeds
    England
    LS9 7TF
  • Princess Royal Hospital
    Hull
    England
    HU8 9HE
  • Guy's and St. Thomas' Hospitals NHS Trust
    London
    England
    SE1 9RT
  • Royal Marsden Hospital - Sutton
    Sutton
    England
    SM2 5PT


The study is sponsored by European Organisation for Research and Treatment of Cancer - EORTC and is in collaboration with National Cancer Institute (NCI); Groupe D'Etude des Tumeurs Uro-Genitales; Institute of Cancer Research, United Kingdom; Central European Cooperative Oncology Group; NCIC Clinical Trials Group; SWOG Cancer Research Network; German Association of Urologic Oncology; Spanish Oncology Genito-Urinary Group; Medical Research Council.




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Read full details for Trial ID: NCT00022191
Last updated 11 June 2013

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