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Be Part of Research - Trial Details - Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder

Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder

Completed

Open to: MALE

Age: 18.0 - 50.0

Medical Conditions

Autistic Disorder
Autism Spectrum Disorder
Child Development Disorders, Pervasive


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study investigates brain response to single acute dose of cannabidiol, cannabidivarin, and placebo in healthy men with and without autism spectrum disorder

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Aug 2016 Feb 2017

Publications

"Pretzsch CM, Floris DL, Voinescu B, Elsahib M, Mendez MA, Wichers R, Ajram L, Ivin G, Heasman M, Pretzsch E, Williams S, Murphy DGM, Daly E, McAlonan GM. Modulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin. Mol Autism. 2021 Jul 1;12(1):49. doi: 10.1186/s13229-021-00454-6."; "34210360"

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Single oral dose of PLC.

Intervention Arm Group : CBD, CBDV, PLC;CBD, PLC, CBDV;CBDV, CBD, PLC;CBDV, PLC, CBD;PLC, CBD, CBDV;PLC, CBDV, CBD;

Intervention Type : DRUG
Intervention Description : Single oral dose of cannabidiol (CBD) - 600mg.

Intervention Arm Group : CBD, CBDV, PLC;CBD, PLC, CBDV;CBDV, CBD, PLC;CBDV, PLC, CBD;PLC, CBD, CBDV;PLC, CBDV, CBD;

Intervention Type : DRUG
Intervention Description : Single oral dose of cannabidivarin (CBDV) - 600mg.

Intervention Arm Group : CBD, CBDV, PLC;CBD, PLC, CBDV;CBDV, CBD, PLC;CBDV, PLC, CBD;PLC, CBD, CBDV;PLC, CBDV, CBD;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • King's College London
    London
    SE5 8AF


The study is sponsored by King's College London




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Read full details for Trial ID: NCT03537950
Last updated 04 March 2024

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