Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Siv Åshild Billington +4797777857
sivwii@sthf.no


Lise Torpen +4790864581
linyto@ous-hf.no


Study Location:

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Be Part of Research - Trial Details - PARASTOP - Paracetamol With Strong Opioids

PARASTOP - Paracetamol With Strong Opioids

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Cancer Pain


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Current guidelines recommend all people with cancer-related pain should be prescribed paracetamol, even those receiving high doses of strong pain killers (opioids) such as morphine. Although this has been shown in studies to be beneficial in other conditions, for instance dental work and after surgery, it has not been shown to further improve pain in people with cancer-related pain. Taking tablets is burdensome to patients and the study aims to determine whether the inconvenience of taking eight extra paracetamol tablets per day can be justified.

The study plans to show whether or not pain control is changed (non-inferior) when stopping paracetamol compared to continued use of paracetamol in people already taking strong pain killers for cancer-related pain. Voluntary participants who are taking a combination of paracetamol and a strong opioid are recruited to the study.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Oct 2021 Jan 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Paracetamol 500 mg

Intervention Arm Group : Paracetamol;

Intervention Type : DRUG
Intervention Description : Placebo

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Edinburgh Cancer Research
    Edinburgh

Siv Åshild Billington +4797777857
sivwii@sthf.no


Lise Torpen +4790864581
linyto@ous-hf.no



The study is sponsored by Oslo University Hospital and is in collaboration with Sykehuset Telemark.




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Read full details for Trial ID: NCT05051735
Last updated 27 February 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.