Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Leane Hodson leanne.hodson@ocdem.ox.ac.uk


David J Dearlove 07739460623
david.dearlove@ocdem.ox.ac.uk


Study Location:

Skip to Main Content
English | Cymraeg
Be Part of Research - Trial Details - Blood Lipid Responses to Diet

Blood Lipid Responses to Diet

Recruiting

Open to: ALL

Age: 18.0 - 65.0

Medical Conditions

Metabolic Diseases


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The macronutrient composition of our diet (proportions of carbohydrates, fats and proteins) strongly influences the way our body stores and utilises substrates (e.g., fats and sugars), which in turn influences our risk of developing cardiometabolic diseases (e.g., coronary artery disease or insulin resistance). The optimal dietary composition to lower the risk of cardiometabolic disease is unknown.

In a randomized, parallel design, this study will investigate how the overconsumption of carbohydrates and fats affects blood lipid responses and liver metabolism in adults free from metabolic disease. By genotyping participants, we will also examine the interaction between macronutrient content and an individual's genes on blood lipid responses and liver metabolism.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Feb 2023 Jan 2028

INTERVENTIONAL

Intervention Type : OTHER
Intervention Description : Eucaloric diet enriched in either carbohydrates or fat (both contributing to 65% total energy intake)

Intervention Arm Group : High carbohydrate, low fat diet;High fat, low carbohydrate diet;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Oxford Centre for Diabetes, Endocrinology and Metabolism
    Oxford
    OX3 7LE
  • Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford
    Oxford
    OX3 7LE


The study is sponsored by University of Oxford




We'd like your feedback

Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.


Is this study information helpful?

What will you do next?

Read full details for Trial ID: NCT05973539
Last updated 19 December 2023

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.