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Be Part of Research - Trial Details - Investigation of 2X-121 in Patients With Advanced Ovarian Cancer Selected by the 2X-121 DRP®

Investigation of 2X-121 in Patients With Advanced Ovarian Cancer Selected by the 2X-121 DRP®

Not Recruiting

Open to: FEMALE

Age: 18.0 - N/A

Medical Conditions

Ovarian Neoplasms
Carcinoma, Ovarian Epithelial


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study is to be performed as an open label, multicenter, single arm study of 2X-121 to evaluate anti-tumor efficacy of 2X-121 as single agent therapy in a 28-days cycle in advanced ovarian cancer patients. 2X-121 will be supplied for oral administration twice daily as 600 mg (3 x 200 mg) capsules in a 28 days cycle. Patients with predicted high likelihood of responding to the drug (2X-121) using drug response prediction (DRP®), will be included in the study.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Apr 2019 Sep 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Every patient will receive daily oral administrations of 3 x 200 mg 2X-121 hard gelatin capsules in a 28-day cycle.

Intervention Arm Group : 2X-121;

Intervention Type : DEVICE
Intervention Description : A DRP is an assay that based on samples from a tumor can predict whether the tumor will respond to a specific drug or not.

Intervention Arm Group : 2X-121;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Guy's and St Thomas' NHS Foundation Trust
    London
    SE1 9TR
  • Beatson West of Scotland Cancer Centre
    Glasgow
    G12 0YN


The study is sponsored by Allarity Therapeutics and is in collaboration with Alcedis GmbH; Amarex Clinical Research.




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Read full details for Trial ID: NCT03878849
Last updated 22 January 2025

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