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Be Part of Research - Trial Details - Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis

Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis

Stopped

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Muscle Spasticity
Multiple Sclerosis
Sclerosis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study will be conducted to evaluate the effect of multiple doses of nabiximols compared with placebo on a clinical measure of velocity-dependent muscle tone in the lower limbs (Lower Limb Muscle Tone-6 \[LLMT-6\]) in participants with multiple sclerosis (MS). LLMT-6 is defined as the average of the 6 individual Modified Ashworth Scale (MAS)-transformed scores of knee flexors, knee extensors, and plantar flexors on both sides of the body.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Aug 2021 Nov 2022

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : oromucosal spray

Intervention Arm Group : Nabiximols;

Intervention Type : DRUG
Intervention Description : oromucosal spray

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Panthera Biopartners - Preston
    Preston
    England
    PR2 9QB
  • Panthera Biopartners - North London
    North London
    England
    EN1 1LJ
  • ReCognition Health - Plymouth
    Plymouth
    England
    PL6 8BT
  • Sheffield Teaching Hospitals NHS Foundation Trust
    Sheffield
    England
    S10 2JF
  • NHS Highland
    Inverness
    Scotland
    IV2 3UJ


The study is sponsored by Jazz Pharmaceuticals




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Read full details for Trial ID: NCT04984278
Last updated 09 December 2024

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