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Be Part of Research - Trial Details - AAV Gene Therapy Screening/Observational Protocol (ECLIPSE)

AAV Gene Therapy Screening/Observational Protocol (ECLIPSE)

Completed

Open to: MALE

Age: 16.0 - N/A

Medical Conditions

Hemostatic Disorders
Hemophilia B
Blood Coagulation Disorders
Blood Coagulation Disorders, Inherited
Hematologic Diseases


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Freeline is developing adeno-associated virus (AAV) vector based gene therapies for a number of diseases and is actively advancing a programme in Haemophilia B (HB). This study aims to collect prospective data to characterise bleeding events and Factor IX (FIX) concentrate consumption in HB patients that can be used as baseline for participants who elect to participate in a subsequent Freeline gene therapy study. The study will also screen participants for antibodies to a novel AAV vector to assess their suitability for inclusion in a Freeline gene therapy treatment study.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Feb 2020 Oct 2022

OBSERVATIONAL



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Queen Elizabeth Hospital
    Birmingham
  • Hammersmith Hospital
    London
  • Glasgow Royal Infirmary
    Glasgow
  • Manchester Royal Infirmary
    Manchester
  • St Thomas' Hospital
    London
  • Royal Free London NHS Foundation Tust
    London
  • The Haemophilia and Thrombosis Centre
    Canterbury
    Kent
  • Cardiff University Hospital
    Cardiff
  • Newcastle Hemophilia Comprehensive Care Centre
    Newcastle


The study is sponsored by Freeline Therapeutics




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Read full details for Trial ID: NCT04272554
Last updated 03 November 2022

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