Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Shay Shemesh, MSc 201 614-3153
sshemesh@nuvectis.com


Diane Marsolini 201 627-8154
dmarsolini@nuvectis.com


Study Location:

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Be Part of Research - Trial Details - A Phase 1 Clinical Study of NXP800 in Subjects with Advanced Cancers and Expansion in Subjects with Ovarian Cancer

A Phase 1 Clinical Study of NXP800 in Subjects with Advanced Cancers and Expansion in Subjects with Ovarian Cancer

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Adenocarcinoma
Ovarian Neoplasms
Carcinoma, Ovarian Epithelial
Carcinoma, Endometrioid
Adenocarcinoma, Clear Cell
Adenomyoepithelioma


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of the dose escalation phase is to evaluate the safety profile of escalating doses and dose schedules of NXP800. In the expansion phase the preliminary efficacy in subjects with ARID1a mutated ovarian clear cell and ovarian endometrioid cancers will be estimated.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Dec 2021 May 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : NXP800 is an anti-neoplastic, oral small molecule.

Intervention Arm Group : Part A: Dose Escalation;Part B: Expansion in Ovarian Cancers Cohort 1;Part B: Expansion in Ovarian Cancers Cohort 2;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Addenbrookes Hospital
    Cambridge
    CB2 0QQ
  • The Beatson West of Scotland Cancer Centre
    Glasgow
    G12 0YN
  • Royal Marsden Hospital
    London Borough of Sutton
    Sutton Surrey
    SM2 5PT


The study is sponsored by Nuvectis Pharma, Inc. and is in collaboration with Gynecologic Oncology Group Foundation; The European Network for Gynaecological Oncological Trial groups (ENGOT).




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Read full details for Trial ID: NCT05226507
Last updated 11 February 2025

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