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Be Part of Research - Trial Details - Study of Meningococcal B Vaccine and ACWY Conjugate Vaccine in Healthy Adults

Study of Meningococcal B Vaccine and ACWY Conjugate Vaccine in Healthy Adults

Completed

Open to: ALL

Age: 18.0 - 65.0

Medical Conditions

Meningitis, Meningococcal
Meningitis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The study involves the measurement of immune response to vaccination with three doses of a meningococcal B vaccine and a single dose of a meningococcal ACYW conjugate vaccine in healthy adults (Laboratory workers). The study will be completed at the Manchester Medical Microbiology Partnership in the UK and will enrol staff who may be at potential occupational exposure to meningococci. Blood samples will be taken before and after each vaccination and used to determine if the vaccines induce protective responses.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2010 Mar 2011

Publications

"Findlow J, Bai X, Findlow H, Newton E, Kaczmarski E, Miller E, Borrow R. Safety and immunogenicity of a four-component meningococcal group B vaccine (4CMenB) and a quadrivalent meningococcal group ACWY conjugate vaccine administered concomitantly in healthy laboratory workers. Vaccine. 2015 Jun 26;33(29):3322-30. doi: 10.1016/j.vaccine.2015.05.027. Epub 2015 May 27."; "26025807"

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Meningococcal B vaccine will be administered at 0, 2 and 6 months and a single dose of meningococcal ACYW vaccine will be administered at 0 months, concomitantly with the first dose of the meningococcal B vaccine.




You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Manchester Medical Microbiology Partnership
    Manchester
    M13 9WZ


The study is sponsored by Prof. Elizabeth Miller and is in collaboration with Novartis Vaccines.




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Read full details for Trial ID: NCT00962624
Last updated 17 September 2018

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