Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Sarah Bradley 01413017540
sarah.bradley@glasgow.ac.uk


Judith Dixon-Hughes 01413302718
judith.dixon@glasgow.ac.uk


Study Location:

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Be Part of Research - Trial Details - PRIMUS 001: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer

PRIMUS 001: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer

Medical Conditions


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study is comparing two combinations of chemotherapy treatments in patients with metastatic pancreatic cancer. Half the participants will receive FOLFOX-A and the other half will receive AG. Treatment will continue until progression or patient/clinican decision or intolerable toxicity.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2017 Dec 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Patients will recieve nab-paclitaxel, oxaliplatin, Folinic Acid and 5-FU in a 14 day cycle

Intervention Arm Group : FOLFOX-A;

Intervention Type : DRUG
Intervention Description : Patients will receive gemcitabine and nab-paclitaxel 3 weeks out of 4

Intervention Arm Group : Abraxane and Gemcitabine;

Intervention Type : DRUG
Intervention Description : Patients in the FOLFOX-A arm will also receive daily G-CSF as primary prophylaxis for all cycles. This will be given as per local site policy for 14 day chemotherapy regimens

Intervention Arm Group : FOLFOX-A;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Huddersfield Royal Infirmary
    Huddersfield
    HD3 3EA
  • The Clatterbridge Cancer Centre
    Liverpool
    CH63 4JY
  • Queen Elizabeth Hospital
    Birmingham
  • St George's Hospital
    London
  • Nottingham University Hospital
    Nottingham
  • University College London Hospital
    London
  • Royal Bournemouth Hospital
    Bournemouth
  • Guy's Hospital
    London
  • Ninewells Hospital
    Dundee
  • Freeman Hospital
    Newcastle
  • Addenbrooke's Hospital
    Cambridge
  • Aberdeen Royal Infirmary
    Aberdeen
  • Beatson West of Scotland Cancer Centre
    Glasgow
  • Churchill Hospital
    Oxford
  • Singleton Hospital
    Swansea
  • Royal Marsden Hospital
    London
  • Poole Hospital
    Poole
  • St James's University Hospital
    Leeds
  • Castle Hill Hospital
    Cottingham
  • Imperial College Healthcare Trust
    London
  • Western General
    Edinburgh
  • Raigmore Hospital
    Inverness
  • Bristol Oncology Centre
    Bristol
  • Northern Ireland Cancer Centre
    Belfast
  • Royal Free London Hospital
    London
  • St Bart's Hospital
    London
  • The Christie, Manchester
    Manchester
  • Weston Park
    Sheffield
  • Milton Keynes General Hospital
    Milton Keynes
  • University of Southampton Hospital
    Southampton


The study is sponsored by Judith Dixon-Hughes and is in collaboration with NHS Greater Glasgow and Clyde; University of Glasgow.





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Read full details for Trial ID: NCT04151277
Last updated 07 February 2024

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