Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Mr Prakash Patel
02071887188
A-Star@gstt.nhs.uk


Prof Carsten Flohr


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - The UK-Irish Eczema Register

The UK-Irish Eczema Register

Medical Conditions

Atopic Eczema


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


Eczema (or dermatitis) is a dry skin condition that can affect people in different forms. It can lead to constant scratching, which causes the skin to split and bleed, and leaves it open to infection.
Eczema can be treated using “systemic immuno-modulators”. People with eczema have an overactive immune system that is inflamed. Immuno-modulators are used to suppress the immune system, which in turn reduces inflammation. As they are systemic, they affect the entire body, rather than just one specific area.
Since eczema is a long-term condition, it is important to understand how well such treatments work in terms of improvement in disease control, quality of life and safety over long periods of time. These treatments have undergone careful clinical trials, but the picture we get from clinical trials is not complete. This project aims to fill the gap in knowledge and collect information from patients using systemic immuno-modulators who attend regular dermatology clinics, to better understand the “real world” use of these medicines. It aims to look at side effects, especially for patients taking medication for other conditions, to increase understanding of the risk of using these therapies. It will also look at the "real cost" of these eczema treatments, to examine how much the therapies cost in the long term compared to how well they work.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Sep 2018 31 Dec 2025

Participants will be asked to complete questionnaires in addition to their usual clinic assessments. They will also be asked to donate an optional DNA sample. The study intends to set up a biorepository, which is where patients will be asked to provide optional blood and skin samples to help us better understand how eczema develops and why therapies work better for some people than others, or cause more side effects in others. Donation to the biorepository is a completely optional section of the study.


Patients with atopic eczema who are about to start a systemic immuno-modulator therapy.

You can take part if:



You may not be able to take part if:


1. Insufficient understanding of the study by the patient and/or parent/guardian.2. Patients who are currently participating in a randomised clinical trial.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University Hospital Southampton NHS Foundation Trust
    Mailpoint 18 Southampton General Hospital Tremona Road
    Southampton
    SO16 6YD
  • Great Ormond Street Hospital For Children NHS Foundation Trust
    Great Ormond Street
    London
    WC1N 3JH
  • Guy's and St Thomas' NHS Foundation Trust
    Trust Offices Guy's Hospital Great Maze Pond
    London
    SE1 9RT
  • University Hospital of Wales
    Cardiff
    CF14 4XW
  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust
    Freeman Hospital Freeman Road High Heaton
    Newcastle
    NE7 7DN
  • Manchester University NHS Foundation Trust
    Corbett House Oxford Road
    Manchester
    M13 9WL
  • Sheffield Teaching Hospitals NHS Foundation Trust
    Northern General Hospital Herries Road
    Sheffield South
    S5 7AU
  • Sheffield Children's NHS Foundation Trust
    Western Bank
    Sheffield South
    S10 2TH
  • University Hospitals Bristol Nhs Foundation Trust
    Marlborough Street
    Bristol Avon
    BS1 3NU
  • Oxford University Hospitals NHS Foundation Trust
    John Radcliffe Hospital Headley Way
    Headington Oxford
    OX3 9DU
  • Royal Hospital for Children
    West Glasgow Ambulatory Care Hospital Dalnair Street Yorkhill
    Glasgow
    G3 8SJ
  • University of Dundee
    Dundee
    DD1 4HN
  • University of Edinburgh
    Department of Dermatology Lauriston Building Lauriston Place
    Edinburgh
    EH3 9HA
  • Trinity College Dublin
    Dublin
    8

There are no additional clinical benefits to participants other than that the information obtained will help the dermatology community better understand the disease and develop more effective treatments in future. There are no known risks to participants taking part in the questionnaire section of the study. For the blood sample collection, the risks may be discomfort and potential bleeding or bruising. For the skin biopsy, the risks include discomfort, infection, scarring, a reaction to local anaesthetic or bleeding.

Mr Prakash Patel
02071887188
A-Star@gstt.nhs.uk


Prof Carsten Flohr



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by King's College London; Guy's and St Thomas' NHS Foundation Trust and funded by British Skin Foundation.




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Read full details for Trial ID: ISRCTN11210918

Or CPMS 38716

Last updated 14 December 2023

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