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Be Part of Research - Trial Details - Multicentre ObservatioNal Initiative in Treat to Target Outcomes in Psoriatic Arthritis
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Multicentre ObservatioNal Initiative in Treat to Target Outcomes in Psoriatic Arthritis

Completed

Open to: ALL

Age: 18.0 - N/A

Oxford

Medical Conditions

Arthritis
Arthritis, Psoriatic

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


MONITOR is a cohort study recruiting patients with a new diagnosis of psoriatic arthritis (PsA) which will establish outcomes using a pragmatic feasible 'treat to target' approach in a real-life clinic population. It is the central cohort for a planned Trials Within Cohorts (TWiCs) design which will test alternative therapies and interventions in embedded clinical trials comparing outcomes to those receiving "standard care" in the cohort.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Apr 2018 Dec 2024

Publications

"Rombach I, Tillett W, Jadon D, Tucker L, Watson M, Francis A, Sinomati Y, Eldridge L, Dritsaki M, Dutton SJ, Al-Mossawi H, Gullick N, Thompson B, Coates LC. Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis-study protocol for the MONITOR-PsA study, a trials within cohorts study design. Trials. 2021 Mar 4;22(1):185. doi: 10.1186/s13063-021-05142-7."; "33663566"

OBSERVATIONAL

Intervention Type : DRUG
Intervention Description : This study is observational and patients will receive treatment for their psoriatic arthritis as clinically indicated. As per standard practice in this observational cohort, patients are most likely to be treated with methotrexate as the most common first line therapy in PsA. This cohort is the basis of a TWiCs (Trials Within Cohorts) study design and interventional studies will be nested within this in future. Whilst the cohort will receive treatment for their PsA as part of their routine clinical care, this treatment will be decided according to routine care and not protocolised.

Intervention Arm Group : Standard care cohort;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Oxford University Hospitals NHS Trust
    Oxford
    Oxfordshire
    OX3 7LD


The study is sponsored by University of Oxford and is in collaboration with National Institute for Health Research, United Kingdom.




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Read full details for Trial ID: NCT03531073
Last updated 21 January 2025

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