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Be Part of Research - Trial Details - Advanced Bolus Calculator for Type 1 Diabetes (ABC4D)

Advanced Bolus Calculator for Type 1 Diabetes (ABC4D)

Completed

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Diabetes Mellitus
Diabetes Mellitus, Type 1


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study aims to assess the safety and efficacy of a novel advanced bolus calculator in subjects with Type 1 diabetes. Insulin bolus calculators have been developed to aid insulin dose adjustment and existing standard insulin bolus calculator consist of a simple algorithm that requires five subject-specific parameters as input to generate a recommended bolus insulin dose:

* current blood glucose (mmol/L) * target blood glucose (mmol/L) * insulin-to-carbohydrate ratio (grams of carbohydrate per 1 unit of insulin) * total grams of carbohydrate in meals * insulin sensitivity factor (reduction in glucose per 1 unit of insulin)

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2013 Oct 2021

Publications

"Reddy M, Pesl P, Xenou M, Toumazou C, Johnston D, Georgiou P, Herrero P, Oliver N. Clinical Safety and Feasibility of the Advanced Bolus Calculator for Type 1 Diabetes Based on Case-Based Reasoning: A 6-Week Nonrandomized Single-Arm Pilot Study. Diabetes Technol Ther. 2016 Aug;18(8):487-93. doi: 10.1089/dia.2015.0413. Epub 2016 May 19."; "27196358"

INTERVENTIONAL

Intervention Type : DEVICE
Intervention Description : Advanced Bolus Calculator for Type 1 Diabetes (ABC4D) to calculate pre-meal insulin boluses

Intervention Arm Group : Phase 4: Intervention (ABC4D);

Intervention Type : DEVICE
Intervention Arm Group : Phase 4 Control: Standard bolus calculator;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Imperial College London, Imperial College Healthcare NHS Trust
    London
    W2 1PG


The study is sponsored by Imperial College London





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Read full details for Trial ID: NCT02053051
Last updated 15 March 2024

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