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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Central Recruiting (+1) 650-538-2502
clinicaltrials@alumis.com


Study Location:

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Be Part of Research - Trial Details - Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

Recruiting

Open to: ALL

Age: 18.0 - 70.0

Medical Conditions

Lupus Erythematosus, Systemic


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to assess the clinical efficacy, safety, PK, and PD of multiple dose levels of ESK-001 compared with placebo in adult patients with SLE.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2023 Jul 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Oral tablet

Intervention Arm Group : ESK-001 Dose Level 1;ESK-001 Dose Level 2;ESK-001 Dose Level 3;

Intervention Type : DRUG
Intervention Description : Oral tablet

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Investigator Site #4017
    Leeds
    LS1 3EX
  • Investigator Site #4015
    London
    NW1 2BU
  • Investigator Site #4016
    London
    SE1 7RT
  • Investigator Site #4014
    Southampton
    SO16 6YD


The study is sponsored by Alumis Inc




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Read full details for Trial ID: NCT05966480
Last updated 03 June 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.