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Be Part of Research - Trial Details - A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

Not Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to evaluate the safety and tolerability of INCB099280 in combination with adagrasib and to establish the MTD or identify RDE(s) for the combination of INCB099280 and adagrasib.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Dec 2023 Nov 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Administered as specified in the treatment arm description

Intervention Arm Group : Part 1: Dose Finding;Part 2: Dose Expansion;

Intervention Type : DRUG
Intervention Description : Administered as specified in the treatment arm description

Intervention Arm Group : Part 1: Dose Finding;Part 2: Dose Expansion;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Hammersmith Hospital
    London
    W12 0HS
  • Guys Hospital
    London
    SE1 9RT


The study is sponsored by Incyte Corporation and is in collaboration with Mirati Therapeutics Inc..




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Read full details for Trial ID: NCT06039384
Last updated 01 May 2025

This page is to help you find out about a research study and if you may be able to take part

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