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Be Part of Research - Trial Details - Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis

Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis

Completed

Open to: ALL

Age: All

Medical Conditions

Vasculitis


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


The purpose of this study is to investigate whether mycophenolate mofetil is effective as treatment for new cases of ANCA associated vasculitis.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Mar 2007 Jul 2011

Publications

"Jones RB, Hiemstra TF, Ballarin J, Blockmans DE, Brogan P, Bruchfeld A, Cid MC, Dahlsveen K, de Zoysa J, Espigol-Frigole G, Lanyon P, Peh CA, Tesar V, Vaglio A, Walsh M, Walsh D, Walters G, Harper L, Jayne D; European Vasculitis Study Group (EUVAS). Mycophenolate mofetil versus cyclophosphamide for remission induction in ANCA-associated vasculitis: a randomised, non-inferiority trial. Ann Rheum Dis. 2019 Mar;78(3):399-405. doi: 10.1136/annrheumdis-2018-214245. Epub 2019 Jan 5."; "30612116"

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : 2-3g/day for 3-6 months, in tablet, capsule or liquid form

Intervention Arm Group : mycophenolate mofetil;

Intervention Type : DRUG
Intervention Description : intravenous cyclophosphamide, 15mg/kg with dose reductions according to age and renal function, for 3-6 months (6-10 doses total)

Intervention Arm Group : cyclophosphamide;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Addenbrookes Hospital
    Cambridge
    Cambridgeshire
    CB22QQ


The study is sponsored by Cambridge University Hospitals NHS Foundation Trust and is in collaboration with Aspreva Pharmaceuticals; Vifor Pharma.




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Read full details for Trial ID: NCT00414128
Last updated 05 December 2013

This page is to help you find out about a research study and if you may be able to take part

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