Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Study Location:

Skip to Main Content
English | Cymraeg
Be Part of Research - Trial Details - Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial

Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial

Completed

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Arthritis
Arthritis, Psoriatic


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


SPEED is a three arm interventional trial nested within a cohort (Trials Within Cohorts or TWiCs design). This tests more aggressive early therapy in patients newly diagnosed with moderate to severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as the control group. Arm 2 will receive early combination conventional synthetic disease modifying anti-rheumatic drugs (csDMARDs). Arm 3 will receive early tumour necrosis factor (TNF) inhibitor therapy.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

May 2019 Oct 2024

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Used in all three arms of study

Intervention Arm Group : Combination csDMARD;Early TNF inhibition;Standard care;

Intervention Type : DRUG
Intervention Description : Used in arm 2 of study

Intervention Arm Group : Combination csDMARD;Standard care;

Intervention Type : DRUG
Intervention Description : Used in arm 2 of study

Intervention Arm Group : Combination csDMARD;Standard care;

Intervention Type : DRUG
Intervention Description : Used in arm 3 of the study only

Intervention Arm Group : Early TNF inhibition;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Oxford University Hospitals NHS Trust
    Oxford
    Oxfordshire
    OX3 7LD


The study is sponsored by University of Oxford





We'd like your feedback

Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.


Is this study information helpful?

What will you do next?

Read full details for Trial ID: NCT03739853
Last updated 21 January 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.