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Be Part of Research - Trial Details - Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration

Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration

Completed

Open to: MALE

Age: 18.0 - 40.0

Medical Conditions


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The objective of this trial is to determine the effects of dietary supplementation with the amino acids, L-arginine and L-citrulline, on endurance performance and mitochondrial respiration in healthy men compared to supplementation with L-arginine alone and a placebo supplement.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

May 2019 Jan 2022

INTERVENTIONAL

Intervention Type : DIETARY_SUPPLEMENT
Intervention Description : Dietary Supplement: L-arginine and L-citrulline supplement, L-arginine supplement, or placebo supplement (corn-starch) Subjects will complete 3 individual 10 day supplementation periods, separated by washout periods of approximately 2 weeks.

Intervention Arm Group : L-arginine;L-arginine and L-citrulline;Placebo (corn-starch);

Intervention Type : BEHAVIORAL
Intervention Description : On day 10 of each supplementation period, subjects will complete a performance test on a cycle ergometer to investigate their endurance performance.

Intervention Arm Group : L-arginine;L-arginine and L-citrulline;Placebo (corn-starch);



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • School of Sport, Exercise and Health Sciences
    Loughborough
    Leicester
    Le11 3YU


The study is sponsored by Loughborough University and is in collaboration with Kyowa Hakko Bio Co., Ltd..




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Read full details for Trial ID: NCT03998800
Last updated 29 April 2022

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