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Contact Information:

Gilead Clinical Study Information Center 1-833-445-3230 (GILEAD-0)
GileadClinicalTrials@gilead.com


Study Location:

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Be Part of Research - Trial Details - Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Breast Neoplasms
Triple Negative Breast Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) versus treatment of physician's choice (TPC) in participants with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express programmed cell death ligand 1 (PD-L1) or in participants previously treated with anti-programmed cell death (ligand or protein) 1 (Anti-PD-(L)1) Agents in the early setting whose tumors do express PD-L1.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2022 Jul 2028

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Administered intravenously

Intervention Arm Group : Sacituzumab Govitecan-hziy (SG);

Intervention Type : DRUG
Intervention Description : Administered intravenously

Intervention Arm Group : Treatment of Physician's Choice (TPC);

Intervention Type : DRUG
Intervention Description : Administered intravenously

Intervention Arm Group : Treatment of Physician's Choice (TPC);

Intervention Type : DRUG
Intervention Description : Administered intravenously

Intervention Arm Group : Treatment of Physician's Choice (TPC);

Intervention Type : DRUG
Intervention Description : Administered intravenously

Intervention Arm Group : Treatment of Physician's Choice (TPC);



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Guy's and Saint Thomas' NHS Foundation Trust
    London
    SE1 9RT
  • Gloucestershire Hospitals NHS Foundation Trust
    Cheltenham
    GL53 7AN
  • Cancer Research UK Beatson Institute
    Glasgow
    G12 0YN
  • University College London Hospitals NHS Foundation
    London
    WC1E 6BT
  • Royal Free London NHS Foundation Trust
    London
    NW2 2QG
  • Leeds Teaching Hospitals NHS Trust
    Leeds
    LS9 7TF
  • Barts Health NHS Trust
    London
    EC1M 6BQ

Gilead Clinical Study Information Center 1-833-445-3230 (GILEAD-0)
GileadClinicalTrials@gilead.com



The study is sponsored by Gilead Sciences





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Read full details for Trial ID: NCT05382299
Last updated 15 May 2025

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