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Contact Information:

Prof Keith Millar
+44 (0)141 211 3939
k.millar@clinmed.gla.ac.uk


Study Location:

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Be Part of Research - Trial Details - Randomised clinical trial of the effects of Total Intravenous Anaesthesia (TIVA: propofol) versus volatile anaesthesia (sevoflurane-nitrous oxide) on children's post-operative cognition, behaviour and physical morbidity

Randomised clinical trial of the effects of Total Intravenous Anaesthesia (TIVA: propofol) versus volatile anaesthesia (sevoflurane-nitrous oxide) on children's post-operative cognition, behaviour and physical morbidity

Not Recruiting

Open to: All Genders

Age: Child

Medical Conditions

Dental caries


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


Not provided at time of registration

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

19 Mar 2007 28 Feb 2010

Interventional

Intervention Type : Drug
Intervention Description : Children will be randomised to separate groups having general anaesthesia with the intravenous agent propofol, or the volatile agent sevoflurane-nitrous oxide. They will perform child-appropriate tests of reaction time, motor control, attention and memory pre-operatively (baseline), post-operatively prior to discharge, and 48 hours later at home.

Between-group comparisons of performance and of post-operative physical morbidity will test the hypothesis stated above.




You can take part if:



You may not be able to take part if:


1. Respiratory disorder2. Learning disability3. Non-fluent English4. Neurological or psychological impairments that would impede cognitive assessment


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Section of Psychological Medicine
    Glasgow
    G12 0XH

This information has not yet been provided by the study team. You'll have an opportunity to discuss any risks and benefits that may be associated with this study prior to consenting to taking part.


The study is sponsored by NHS Glasgow and Clyde/University of Glasgow and funded by Chief Scientist Office of the Scottish Executive Health Department (UK) (Grant ref: CZH/4/382).




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Read full details for Trial ID: ISRCTN33376683
Last updated 18 April 2016

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