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Be Part of Research - Trial Details - A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

Stopped

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Nephritis
Lupus Nephritis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to assess the efficacy and safety of zetomipzomib (30 mg or 60 mg) compared with placebo in achieving renal response after 52 weeks of treatment in patients with active lupus nephritis (LN).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2023 May 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Subcutaneous injection of zetomipzomib

Intervention Arm Group : zetomipzomib 30 mg + standard-of-care;zetomipzomib 60 mg + standard-of-care;

Intervention Type : DRUG
Intervention Description : Subcutaneous injection of placebo

Intervention Arm Group : placebo + standard-of-care;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Hammersmith Hospital
    London
    W12 0HS
  • Leicester General Hospital
    Leicester
    LE5 4PW
  • Salford Royal NHS Foundation Trust
    Salford
    Greater Manchester
    M6 8HD
  • St. Georges University Hospitals
    London
    SW17 0QT
  • Churchill Hospital
    Headington
    Oxford
    OX3 7LJ
  • Sunderland Royal Hospital
    Sunderland
    Tyne And Wear
    SR4 7TP
  • Royal Derby Hospitals, University Hospitals of Derby and Burton
    Derby
    Derbyshire
    DE22 3NE
  • King's College Hospital
    London
    UK
    SE5 9RS


The study is sponsored by Kezar Life Sciences, Inc.




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Read full details for Trial ID: NCT05781750
Last updated 08 October 2024

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