Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559
clinical_inquiry_hub@lilly.com


Study Location:

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Be Part of Research - Trial Details - A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Medical Conditions

Breast Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy in participants with early breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have already taken endocrine therapy for two to five years and must have a higher-than-average risk for their cancer to return. Study participation could last up to 10 years.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Oct 2022 Oct 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Administered orally.

Intervention Arm Group : Imlunestrant;

Intervention Type : DRUG
Intervention Description : Administered per local approved label.

Intervention Arm Group : Investigator's Choice of Endocrine Therapy;

Intervention Type : DRUG
Intervention Description : Administered per local approved label.

Intervention Arm Group : Investigator's Choice of Endocrine Therapy;

Intervention Type : DRUG
Intervention Description : Administered per local approved label.

Intervention Arm Group : Investigator's Choice of Endocrine Therapy;

Intervention Type : DRUG
Intervention Description : Administered per local approved label.

Intervention Arm Group : Investigator's Choice of Endocrine Therapy;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Lister Hospital
    Stevenage
    SG1 4AB
  • Royal Berkshire Hospital
    Reading
    RG1 5AN
  • Western General Hospital
    Edinburgh
    EH4 2XU
  • Colchester General Hospital
    Colchester
    CO4 5JL
  • Mount Vernon Hospital
    Northwood
    HA6 2RN
  • Clatterbridge Cancer Centre - Liverpool
    Liverpool
    L7 8YA
  • Panthera Biopartners - Preston
    Preston
    PR2 9QB
  • Panthera Biopartners - Manchester
    Rochdale
    OL11 4AU
  • Hairmyres Hospital
    East Kilbride, Glasgow
    G75 8RG
  • St Bartholomew's Hospital
    London
    EC1A 7BE
  • The Christie NHS Foundation Trust
    Manchester
    M20 4BX
  • Derriford Hospital
    Plymouth
    Pl6 8DH
  • Oncology Research
    Wigan
    WN1 2NN

There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559
clinical_inquiry_hub@lilly.com



The study is sponsored by Eli Lilly and Company





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Read full details for Trial ID: NCT05514054
Last updated 26 August 2025

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