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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Shanaz
Jamil-Copley
Shahnaz.jamil-copley@nuh.nhs.uk
Dr
Shanaz
Jamil-Copley
Shahnaz.jamil-copley@nuh.nhs.uk
Shahnaz
Jamil-Copley
s.jamil-copley@nhs.net
Other forms of heart disease
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Ventricular Tachycardia (VT) is a life-threatening rhythm condition often caused by abnormal conduction of electrical activity within heart muscle scarring. Treatment is challenging with medication not always sufficient. Subsequently, patients may require procedures aimed at identifying and burning areas of scarring within the heart to stop this abnormal electrical conduction (ablation).
Ablation procedures utilise wires with sensors to generate a map of the heart with location and paired electrical data. Unfortunately, procedures can be long, challenging if sufficient data is to be collected. For patients, even post-procedure, recurrence of VT is not uncommon.
Magnetic resonance imaging (MRI) of the heart can highlight areas of scar pre-procedural that could be targeted and have been shown to improve patient outcomes. In addition to the identification of scar location, 3D meshes of the heart from MRIs can be imported into the procedural mapping software as a navigational aide.
Therefore, there is the opportunity to correlate pre-procedural MRI features with those found intra-procedurally potentially improving the identification of critically abnormal areas to ablate.
However, due to challenges in data collection at MRI and during procedures, there can be differences between the images generated. This may be further affected by progression in disease in the time between scanning and undertaking the procedure. Currently, it is not clear how to best compare and analysis the data between the modalities.
We propose to develop tools to allow analysis and comparison of these modalities. Using pre-existing patient data of people who have undergone VT ablation procedures locally, we will explore methods to compare and analyse data for use in future studies. Participants will not need to undergo further procedures or interventions as pre-existing data will be used.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Cross-sectional;
You can take part if:
You may not be able to take part if:
Atrial only procedure Absence of saved procedural data Age< 18 years old Deceased
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Shahnaz
Jamil-Copley
s.jamil-copley@nhs.net
Dr
Shanaz
Jamil-Copley
Shahnaz.jamil-copley@nuh.nhs.uk
Dr
Shanaz
Jamil-Copley
Shahnaz.jamil-copley@nuh.nhs.uk
The study is sponsored by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST and funded by Medical Research Council (MRC) .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 58235
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
