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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Christian
Hedrich
christian.hedrich@liverpool.ac.uk
Christian
Hedrich
chedrich@liverpool.ac.uk
Other osteopathies
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
This project will improve our understanding of disease mechanisms and potential future treatment targets in CNO, but also other inflammatory diseases associated with increased P2X7R activity and resulting inflammation and bone loss, such as rheumatoid arthritis, systemic lupus, and others. Lastly, it will establish state-of-the-art human tissue culture models to replace animal models in bone immunology.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Genetic epidemiology;
You can take part if:
You may not be able to take part if:
a) Collection of excess bone tissue from osteotomy surgery Exclusion criteria: • Co-existing osteopenia, etc. through immobilization • Patient or family cannot consent due to limited language skills (in the absence of interpreter service) or limited mental capacity/developmental delay b) Collection of PBMCs from CNO patients and controls Exclusion criteria: • Treatment with pamidronate or other bisphosphonate in the past 9 months • Patient or family cannot consent due to limited language skills (in the absence of interpreter service) or limited mental capacity/developmental delay
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by University of Liverpool and funded by NIHR Great Ormond Street Biomedical Research Centre .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 57726
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
