Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Nicholas Shenker
nicholas.shenker@nhs.net


Geoff Woods
cw347@cam.ac.uk


Ully Gul
enquiries-pain@medschl.cam.ac.uk


Jason Crawte
enquiries-pain@medschl.cam.ac.uk


Jimena Teran Perez
jt861@cam.ac.uk


Jimena Teran Perez
enquiries-pain@medschl.cam.ac.uk


Study Location:

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Be Part of Research - Trial Details - Clinical ADVANTAGE Study

Clinical ADVANTAGE Study

Recruiting

Open to: Female / Male

Age: 18 Years - N/A

Medical Conditions

General symptoms and signs


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


One in twenty individuals in the UK are disabled by visceral pain - approximately as many people as live in the entire country of Wales. The condition is a terrible burden for those who suffer from it: causing pain not only during the most intimate moments of their lives, but also frequently triggering unpredictable episodes of pain "flares" that can need hospital admission.
There are many conditions associated with visceral pain including: chronic pancreatitis, chronic pelvic pain syndrome, endometriosis, inflammatory bowel disease, painful bladder syndrome, autosomal dominant polycystic kidney disease and vaginal mesh surgery.
This study is a collaboration between expert patients and clinicians, clinical and pre-clinical pain researchers, engineers, and industrial collaborators who are working together to try to develop new drugs and treatments – specifically tailored for chronic visceral pain.
We will be looking for people with chronic visceral pain, particularly those who have severe pain despite few signs of disease. We will also look for those who feel little no or pain despite advanced disease. We will record their pain using standard questionnaires but will also explore other ways to capture their experience; for example, using online apps and body sensors to record physical activity and physiological changes, for example heart rate, throughout the day. We hope to discover genes in humans that control pain. We also look to see if the immune system is involved.
Our aim is to improve our understanding of visceral pain from the perspective of people living with the condition, so that the NHS can develop and offer patients more effective interventions and support to address the diverse nature of their symptoms and help improve their quality of life.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

20 Nov 2023 30 Jun 2026

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


Remote mobile app study: -Not able to fulfil inclusion criteria. Wearable sensor study: -Unable to attend or visit the research site. -Travel abroad in the plan duration of wearable sub-study.  -Unable or unwilling to use body sensor for any reason (e.g. contact dermatitis over wear zone, implanted pacemaker or defibrillator, allergy or hypersensitivity to nickel).   Bio-samplings study: -Not able to fulfil inclusion criteria. -Unable to attend or visit the research site.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Addenbrooke's Hospital
    Cambridge
    Cambridgeshire
    CB2 0QQ
  • Royal Infirmary Of Edinburgh At Little France
    Edinburgh
    Lothian
    EH16 4SA


The study is sponsored by CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST and funded by Medical Research Council (MRC) .




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for Trial ID: CPMS 56758

Last updated 21 November 2024

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