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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
James
Norman
j.norman1@nhs.net
Sally
Benton
sally.benton@nhs.net
James
Norman
j.norman1@nhs.net
Other diseases of intestinesBenign neoplasmsMalignant neoplasms of digestive organs
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
The main aim of this study is to determine whether single, or multiple, Faecal immunochemical tests for faecal haemoglobin (F-Hb) and faecal calprotectin (FC) results after an episode of a colorectal condition called acute diverticulitis can be used to risk stratify for further investigations to exclude colorectal cancer. If this is the case it could be used to identify a cohort of patients that don’t need further investigations for colorectal cancer.
The current practice is that this cohort of patients often have further investigation with either a colonoscopy, flexible sigmoidoscopy or computerised tomography colonography which are expensive and invasive procedures with potential serious complications, although these are rare. The faecal immunochemical test for Hb (FIT) has be demonstrated to have a very good negative predictive value in both screening and symptomatic clinics for colorectal cancer.
We will also be aiming to evaluate if F-Hb and FC results relate to other important findings in the colon such as high risk adenomas, evaluating the benefit of additionally using age or anaemia (from bloods taken as part of routine clinical care) to risk stratify and to assess the faecal microbiome following an episode of acute diverticulitis and how it changes as the inflammation settles.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Validation of outcome measures;
You can take part if:
You may not be able to take part if:
Paediatric patients (< 18 years) Not provided at least 1 FIT sample Unable to/unwilling to provide informed consent Withdrawal of consent for inclusion in study Previous pan-proctocolectomy, subtotal colectomy surgery, or presence of stoma Currently being treated for colorectal cancer Mental health illness limiting compliance Treated in hospital with colonic resection Did not have colonoscopy, flexible sigmoidoscopy or CT colonoscopy
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by ROYAL SURREY COUNTY HOSPITAL NHS FOUNDATION TRUST and funded by University of Surrey; GUTS; .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 55623
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
