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Contact Information:

Dr Pippa Bailey
pippa.bailey@bristol.ac.uk


Dr Pippa Bailey
pippa.bailey@bristol.ac.uk


Study Location:

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Be Part of Research - Trial Details - IN-FAKT: INvestigating FAiling Kidney Transplants

IN-FAKT: INvestigating FAiling Kidney Transplants

Completed

Open to: Female / Male

Age: 18 Years - 99 Years

Medical Conditions

Renal failure
Complications of surgical and medical care, not elsewhere classified


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Kidney transplantation is the best treatment for most people with kidney failure. However, kidney transplants rarely work for the whole of a patient’s life. A kidney transplant is said to have failed when it no longer works well enough to keep someone healthy, and another treatment, like dialysis, is required.

Many decisions need to be made when a kidney transplant fails, including whether the transplant should be removed, and which medication should be stopped. There is limited poor-quality evidence on which to base these decisions, and people are managed differently at different hospitals.

We aim to understand:
- patient and family experiences of kidney transplant failure
- patient and family priorities when a transplant fails
- patient, family and healthcare professional beliefs about the best treatment for transplant failure
- how and why decisions regarding failing transplants are made between patients, their families and clinicians
- views on a possible clinical trial to compare different treatments for transplant failure

Through this understanding we hope to learn:
- what outcomes matter most to patients and their families when a transplant fails
- whether healthcare professionals are uncertain how to manage someone with a failing transplant
- what sort of management interventions and clinical trial designs patients and healthcare professionals would support

We will interview 25-30 people who have experienced kidney transplant failure, 25-30 their family, and 10-15 healthcare professionals. We will interview people of different ages, sexes, and ethnicities, with different transplants, different experiences of treatments before and after transplantation, from different UK hospitals. We will investigate whether people’s experiences and views are similar or different, and whether who they are and how they are treated impacts on their experiences.

Findings will be used to inform the design and delivery of a trial to determine the best management for failing transplants.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

03 Aug 2023 31 Aug 2024

Observational

Observational type: Qualitative;



You can take part if:



You may not be able to take part if:


Individuals who lack the Mental Capacity to consent to participation, as deemed by their usual healthcare team, will not be eligible to participate.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Southmead Hospital
    Southmead Road
    westbury-on-trym
    Bristol
    Avon
    BS10 5NB

Dr Pippa Bailey
pippa.bailey@bristol.ac.uk


Dr Pippa Bailey
pippa.bailey@bristol.ac.uk



The study is sponsored by NORTH BRISTOL NHS TRUST and funded by NIHR Central Commissioning Facility (CCF) .





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for Trial ID: CPMS 55003

Last updated 01 May 2025

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