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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Andreas Goebel
andreasgoebel@rocketmail.com


Katy Plant
kmplant@liverpool.ac.uk


Katy Plant
kmplant@liverpool.ac.uk


Rebecca Mountford
R.mountford@liverpool.ac.uk


Study Location:

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Be Part of Research - Trial Details - Fibromyalgia And Refractory pain in Rheumatic diseases Study

Fibromyalgia And Refractory pain in Rheumatic diseases Study

Recruiting

Open to: Female / Male

Age: 18 Years - N/A

Medical Conditions

Inflammatory polyarthropathies
Spondylopathies
Systemic connective tissue disorders


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


Fibromyalgia syndrome is a widespread chronic pain condition affecting 2-5 % of the world population. The causes of fibromyalgia syndrome are currently unknown. Therefore, treatment options are unsatisfactory, and many patients suffer from unrelenting pain without relief.
Recent research from our group suggests that patients may have immune substances, ‘autoantibodies’, in their blood, which contribute to causing their symptoms. Fibromyalgia is diagnosed in about 20-30% of patients suffering from rheumatological conditions. We wish to assess whether the immune contribution observed in Fibromyalgia patients is responsible for widespread pain in patients diagnosed with rheumatic diseases.
Therefore, we will identify patients with either Rheumatoid Arthritis, Axial Spondyloarthritis or Behçet’s Syndrome. One hundred and fifty patients will be recruited half of which will also have a diagnosis of Fibromyalgia Syndrome. Participants will be asked a series of questions and to complete questionnaires. They will have their skin sensitivity measured using a pressure device and brush to the skin. They will also have images of the front of their eye taken and will donate a blood sample. All of the above will occur during a single visit, in which compensation will be provided for travel. The immune substances from the blood sample will be measured and use in laboratory mouse models to assess their role in widespread pain.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

13 Mar 2023 13 Mar 2026

Observational

Observational type: Cross-sectional;



You can take part if:



You may not be able to take part if:


•Pregnant or breast feeding participants •Participants without adequate understanding of the English language •Under the age of 18


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University Hospital Aintree
    Lower Lane
    Liverpool
    Merseyside
    L9 7AL
  • The Walton Centre NHS Foundation Trust
    Lower Lane
    fazakerley
    Liverpool
    Merseyside
    L9 7LJ


The study is sponsored by University of Liverpool and funded by Medical Research Council (MRC) .




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for Trial ID: CPMS 54810

Last updated 20 February 2024

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