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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Sophie
Webster
Sophie.webster3@nhs.net
Katherine
Clark
katherine.clark@kcl.ac.uk
Renal failureOther maternal disorders predominantly related to pregnancy
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Acute Kidney Injury (AKI) is the sudden loss of kidney function that makes people more likely to develop long-term kidney and heart problems and can even lead to death. About one-third of AKI cases are preventable. The number of pregnant women with AKI has increased but we do not know how many or which women are affected. AKI is usually detected by measuring a reduction in urine production or rise in blood creatinine (a marker of kidney function).
The kidney's work about 50% harder during pregnancy making AKI more difficult to detect because creatinine levels are often low. If we can work out which pregnant women are at risk of AKI then we can change their treatment early. Testing of creatinine from a finger prick blood test has been found to reduce AKI outside pregnancy because results are available immediately. A new urine test to predict AKI has also been shown to be useful in non-pregnant patients, but neither test has been studied in pregnancy.
This study aims to check whether women and midwives are willing to use finger-prick and urine tests to predict AKI. I plan to recruit around 550 women including some women with extra risk factors for AKI (e.g. infection) and ask them for finger-prick and urine tests. I will ask them how they feel about the tests. I will ask health care professionals if they think the new tests are helpful. The study findings will be used to design a future trial to reduce AKI in pregnancy.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Validation of outcome measures;
You can take part if:
You may not be able to take part if:
Any Pr-AKI risk factors including: - Chronic Kidney Disease - Hypertension/Pre-eclampsia/Haemolysis, Elevated Liver Enzymes, Low Platelets (HELLP) Syndrome - Suspected infection - Haemorrhage (including concealed) - Acute fatty liver of pregnancy - Urological injury - Urinary tract obstruction - Nephrotoxic exposure Already established on haemodialysis or peritoneal dialysis
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by King's College London and funded by KIDNEY RESEARCH UK .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 54416
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