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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Benign neoplasmsMelanoma and other malignant neoplasms of skin
This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.
The skin is made up of a limited number of cell types. However, these limited cell types could turn into a diverse range of benign and cancerous skin tumour (growth). The overall aim of the study is to understand the relationship between the clinical appearance, microscopic appearance and genetic characteristics of skin tumour (many of which shared similar characteristics and can be difficult to distinguish) in order to refine existing diagnostic criteria for different skin tumour. There will be sub-studies within the overall study which specifically investigates tumour with shared characteristics. Sub-study 1 will investigate keratoacanthoma (grows rapidly and then typically regresses) and cutaneous squamous cell carcinoma (a cancer that keeps growing), which shared similar clinical and microscopic characteristics but have distinctive clinical behaviour. We will apply for major amendment when additional sub-studies are to be added within this research ethics application. The overall study aims to recruit 1000 participants and study methodology involves obtaining patient’s prospective consent for collecting data from their hospital records relevant to their skin tumour and retrieval of their surplus skin tumour tissues stored in NHS diagnostic archive in order to describe their clinical and microscopic characteristics. Participants can opt-in for their pseudo-anonymised tissue samples to be send for genetic analysis (e.g. examine the expression of genes within the neoplasm and adjacent normal skin); opt-in for their anonymised research data to be used for future training of artificial intelligence systems to recognise skin tumour; opt-in for their research data and surplus tissue samples stored in NHS diagnostic archive to be accessed for future research ethics committee approved studies. Descriptive statistical analysis will be performed to describe the correlation between the clinical, microscopic and genetic characteristics of the skin tumour.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Clinical Laboratory Study;
You can take part if:
You may not be able to take part if:
Overall study exclusion criteria • Any inclusion criteria not met • Adult patients that lack capacity to consent to take part in the study
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by SOUTH WARWICKSHIRE UNIVERSITY NHS FOUNDATION TRUST and funded by British Skin Foundation .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 52931
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