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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof Mary Rutherford
mary.rutherford@kcl.ac.uk


Aniqa Tasnim
aniqa.tasnim@kcl.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - MEERKAT

MEERKAT

Recruiting

Open to: Female

Age: 16 Years - 55 Years

Medical Conditions

Disorders related to length of gestation and fetal growth
Maternal care related to the fetus and amniotic cavity and possible delivery problems
Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Magnetic Resonance Imaging is widely used for the antenatal diagnosis and monitoring of pregnancy complications and fetal abnormalities. However, currently, the image quality - and thus ability to accurately and timely diagnose and risks can be hampered by dynamic effects during the scan such as fetal motion, contractions and fetal breathing exercises. The rise in comorbidities such as hypertension and obesity contributes to a rise in pregnancy complications such as pre-eclampsia, preterm birth and fetal growth restriction. It calls as well for a more personalized antenatal diagnosis and treatment. Better and earlier identification of these major risks will help reduce the burden for both mothers and children during and after pregnancy.

We aim to include Doppler Ultrasound (DUS) Information from an MRI compatible DUS and image information in real-time to steer the MRI scan better to safely study the fetus, placenta and surrounding maternal tissues. The information from contractions, movements and fetal breathing exercises gives additional personalized and important information.

We will recruit both healthy pregnant women as controls, women at high-risk for PE (most notably due to chronic hypertension), FGR, preterm birth and with previous uterine surgery.

UKRI funds this research and it will be carried out over a period of 4 years at St. Thomas' Hospital in London on clinical MRI scanners. Participants will be invited for up to four MRI scans during pregnancy and fetal ECG recordings obtained. Their placenta will be analysis after delivery and outcome information obtained.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

13 Jan 2022 30 Jun 2027

Observational

Observational type: Cross-sectional;



You can take part if:



You may not be able to take part if:


Participants under the age of 16 and participants over the age of 55. Participants with clear contra-indication for MRI scan. In particular, this would be due to the presence of any non-MR safe implanted devices or not-MR compatible safe metal from previous surgery or accident.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • St Thomas' Hospital
    Westminster Bridge Road
    London
    Greater London
    SE1 7EH

Aniqa Tasnim
aniqa.tasnim@kcl.ac.uk


Prof Mary Rutherford
mary.rutherford@kcl.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by King's College London and funded by Medical Research Council (MRC) .




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for Trial ID: CPMS 50799

Last updated 25 April 2025

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