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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Injuries to unspecified part of trunk, limb or body region
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Neuropathic pain is a common long-term problem following a spinal cord injury. Studies show that chronic pain has a significant detrimental impact on an individual’s quality of life, ability to manage their daily activities and emotional well-being. Despite treatment by pain specialists, there remains a proportion of patients with refractory pain for whom there are no more options.
We propose to determine whether a procedure called cingulotomy, in essence the cutting of targeted brain pathways involved in regulating chronic pain, could help these most difficult to treat cases. This procedure is a form of stereotactic neurosurgery, which is able to target a specific region of interest in the brain with submillimetre accuracy. A thin wire is guided carefully to the target, the tip of which is then heated by radio-waves to cause a small, focal lesion (area of damage), and thus in effect cut the relevant overactive nerve pathways.
The safety and efficacy of this procedure has been established in a number of different causes of neuropathic pain, but there remains only limited evidence of its use in spinal cord injury. We aim to establish if this is safe and effective in this group of patients.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Type: Active Monitoring;
You can take part if:
You may not be able to take part if:
Traumatic brain injury Severe cognitive impairment Significant medical co-morbidity (e.g. coagulopathy) Radiofrequency lesioning or MRI incompatible device (e.g. baclofen pump or spinal cord stimulator) already in situ
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by St. George's Hospital Medical School and funded by STOKE MANDEVILLE SPINAL RESEARCH .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 49541
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