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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Rachel
Harwood
Rachel.Harwood@alderhey.nhs.uk
Rachel
Harwood
Rachel.Harwood@alderhey.nhs.uk
Provisional assignment of new diseases of uncertain etiology
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The Lateral Flow Antigen Validity and Applicability (LAVA) 2 study aims to determine the validity of lateral flow antigen devices (LFDs) used to perform point of care testing for COVID-19, compared to the current gold standard test of RT-PCR in children.
In a pilot study we have shown that the anterior nose swabs used to perform a LFD test are associated with significantly lower pain scores than the nose and throat swabs used to perform RT-PCR tests and that the results are available significantly more quickly. RT-PCR is an excellent diagnostic test but one drawback includes remaining positive for a prolonged period, potentially when the person is no longer infective, as it can pick up viral particulate rather than live virus. LFDs are more likely to be positive at the point that a person has a high viral load and is therefore infectious to others, but this has not been studied in non-laboratory settings in children. The study aims to determine the correlation between LFD and viral load detected on RT-PCR in children to enable the utility of the test in different clinical and non-clinical settings to be better determined.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Type: Device;
You can take part if:
You may not be able to take part if:
None
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by ALDER HEY CHILDREN'S NHS FOUNDATION TRUST and funded by DEPARTMENT OF HEALTH AND SOCIAL CARE .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 48030
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