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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Adult patients with heart failure and cardiac implantable electronic devices (CIED)
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Many people in the North East and North Cumbria in England (UK) have heart failure, some of whom will also suffer with depression. Having both conditions is particularly challenging. It means you are more likely to have a worse quality of life, feel more fatigued and more likely to need hospital treatment for your heart failure. It also increases the chances of poor outcomes, such as heart transplant or death. It is much harder to diagnose depression in people with heart failure, so you may be less likely to access specialist mental health support. Also, the usual treatments for depression (talking therapies and medication) do not appear to be helpful in patients with heart failure.
The autonomic nervous system controls the unconscious activity in our body. It has an important role in regulating heart rate. Normally there is variation to the heart rate: sometimes the heart beats a little faster and sometimes a little slower. We call this ‘heart rate variability’ and it is a sign of a healthy heart. Heart rate variability is often reduced in heart failure and in depression. Therefore, we wonder if dysregulation of the autonomic nervous system is an important link between heart disease and mood, leading to worse outcomes.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
1. Previous diagnosis of bipolar affective disorder, psychotic disorder or personality disorder.2. Previous diagnosis of dementia.3. Previous diagnosis of primary neurological injury (eg, anoxic injury, stroke or traumatic brain injury) or disorder (eg, Parkinson’s disease).4. Myocardial infarction (MI) within the previous 3 months. 5. Not fluent in English.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Alan
Bagnall
+44 1912137135
alan.bagnall@nhs.net
The study is sponsored by Newcastle upon Tyne Hospitals NHS Foundation Trust and funded by Newcastle upon Tyne Hospitals Charity and Join Research Executive Scientific Committee Research Grant.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
