Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr daniel blackburn
d.blackburn@sheffield.ac.uk


Dr daniel blackburn
d.blackburn@sheffield.ac.uk


Dora Braun
d.a.braun@sheffield.ac.uk


Helen Casbolt
helen.casbolt@nhs.net


Alessia Dunn
alessia.dunn@nhs.net


Jonathan Gardner
jonathan.gardner6@nhs.net


Alessia Dunn
alessia.dunn@nhs.net


Study Location:

Skip to Main Content
English | Cymraeg
Be Part of Research - Trial Details - CognoSpeak

CognoSpeak

Medical Conditions

Cerebrovascular diseases
Extrapyramidal and movement disorders
Organic, including symptomatic, mental disorders


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The aim of this study is to understand whether patients with either memory complaints, suspected movement disorders, such as Parkinson’s disease, people who have suffered a Stroke and healthy volunteers can talk to computerised doctor (CognoSpeak) regarding their neurological health. CognoSpeak is a computerised person i.e. human looking computer generated image that will ask the participant questions regarding their health. In this study CognoSpeak will not be able to respond to the participant answers but the answers can be analysed by a person or a computer to look for features of speech and interaction seen in dementia or other memory disorders. This study will also collect healthy people to speak to CognoSpeak, so that the study team can compare the patient data to a group of participants with no cognitive complaints.

The study will look into how people with memory problems talk about their experiences and difficulties they may have in daily life because of their memory problems.

At present it often takes a long time before memory problems are diagnosed accurately. The results of this study could feed into future clinical trials of efficacy, tolerability and feasibility of utilising CognoSpeak as a cognitive diagnostic aid. This in turn could allow doctors to diagnose the causes of memory problems more accurately and more quickly by using this computer system to ask questions and record answers about their memory problems.

In an earlier study, the study team have shown that examining how people with memory complaints can help distinguish dementia from other types of memory problems such as those due to excessive worry. This study is to further develop CognoSpeak to measure mood and cognition over a long period of time and in different patient groups.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

24 Jun 2020 30 Jun 2026

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


Exclusion Criteria (applies to all patient groups): 1. People who lack the capacity to give informed consent. 2. People who are unable to communicate and understand written or spoken English sufficiently enough to follow the consent process. 3. People with very impaired speech production, such as severe dysphasia. 4. People with severe motor impairment that means they cannot respond to questions or ask for next question even with help of care-partner. Healthy Controls Exclusion Criteria: 1. Presence of neurodegenerative disease (all listed above). 2. Medical condition that would limit potential to take part in longer term follow-up (including palliative diagnosis (including cancer, heart failure, COPD)). 3. Severe active psychiatric disease including Schizophrenia and severe depression. Mild cases would be considered as are encountered in memory clinics with people with memory complaints.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • York Hospital
    York
    North Yorkshire
    YO31 8HE
  • Southampton General Hospital
    Southampton
    Hampshire
    SO16 6YD
  • Doncaster Royal Infirmary
    Doncaster
    South Yorkshire
    DN2 5LT
  • Royal Hallamshire Hospital
    Sheffield
    South Yorkshire
    S10 2JF
  • Southmead Hospital
    Bristol
    Avon
    BS10 5NB
  • Warneford Hospital
    Oxford
    Oxfordshire
    OX3 7JX
  • West London NHS Trust
    Southall
    UB2 4SD
  • St Nicholas Hospital (newcastle Upon Tyne)
    Newcastle Upon Tyne
    Tyne And Wear
    NE3 3XT
  • Kendray Hospital
    Barnsley
    South Yorkshire
    S70 3RD
  • Gmw Trust Headquarters
    Manchester
    Greater Manchester
    M25 3BL
  • Doncaster - Tickhill Road Site
    Doncaster
    South Yorkshire
    DN4 8QN
  • Central & North West London NHS Foundation Trust Headquarters
    London
    Greater London
    NW1 7QY
  • MEMORY CLINIC 101768

Dr daniel blackburn
d.blackburn@sheffield.ac.uk


Jonathan Gardner
jonathan.gardner6@nhs.net


Dora Braun
d.a.braun@sheffield.ac.uk


Alessia Dunn
alessia.dunn@nhs.net


Alessia Dunn
alessia.dunn@nhs.net


Dr daniel blackburn
d.blackburn@sheffield.ac.uk


Helen Casbolt
helen.casbolt@nhs.net



The study is sponsored by SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST and funded by Engineering and Physical Sciences Research Council (EPSRC); University of Sheffield; ROSETREES; .




We'd like your feedback

Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.


Is this study information helpful?

What will you do next?

Read full details

for Trial ID: CPMS 45131

Last updated 07 July 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.