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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Megan
Cartier
megan.cartier@nhs.net
Prof
Andrew
Lotery
a.j.lotery@soton.ac.uk
Mrs
Angela
Cree
a.j.cree@soton.ac.uk
Disorders of choroid and retina
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Age-related-macular-degeneration (AMD) is a very common cause of blindness. Unfortunately,doctors don’t know who will progress to the sight threatening stage of the disease. Some patients progress slowly or not at all and others quickly.
We can teach computers to analyse high resolution images of the inside of the eye. We have access to hundreds of thousands of such images from patients with AMD and patients who don’t have AMD. These images allow us to train computers to identify what eye changes appear in patients with AMD. Once the computers have learnt this, we expect they will identify new changes we haven’t thought of.
Using this approach we think we will be able to better predict which patients will progress. This should help us develop better treatments and enter the most appropriate patients into clinical trials. It should allow us to better understand why AMD develops too.
We would like to image the eyes of 400 AMD patients regularly over a 3 year period. Using machine learning techniques, these images will be collated and used alongside existing images from previous studies and the UK Biobank to help develop a method of predicting disease development and progression in AMD. To assist with this, we would also like to take a blood sample for genetic testing in order to allow for any genetic factors that may affect the progression pathway.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Validation of outcome measures;
You can take part if:
You may not be able to take part if:
Exclusion criteria: 1. Co-existent ocular disease, which might affect visual function or retinal morphology 2. Cataract sufficient to affect retinal imaging 3 Major ocular surgery 3 months prior or anticipated within the next 6 months following enrolment. 4 Taking drugs known to cause retinal toxicity
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Mrs
Angela
Cree
a.j.cree@soton.ac.uk
Megan
Cartier
megan.cartier@nhs.net
Prof
Andrew
Lotery
a.j.lotery@soton.ac.uk
The study is sponsored by University of Southampton and funded by Wellcome Trust .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 41819
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
