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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Sandra Strauss
s.strauss@ucl.ac.uk


ICONIC Trial Coordinator
ctc.iconic@ucl.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - ICONIC

ICONIC

Completed

Open to: Female / Male

Age: 0 Years - N/A

Medical Conditions

Malignant neoplasms of bone and articular cartilage


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


There has been little improvement in outcome for patients with osteosarcoma (OS) over the last 20 years. There have been only a few clinical trials of new treatments and no major new therapies introduced recently. This is in part because we do not have a good understanding of the biology of osteosarcoma, but also trials have only included subgroups of patients. The more we understand about how and why osteosarcoma arises and grows the better we will be able to decide what treatments are most likely to work best.

The purpose of this project is to collect high quality clinical data about patients of all ages with osteosarcoma, such as information about the size of the disease, how it was diagnosed and where it is at diagnosis, what treatments were given and how the disease responded the treatments. We will also collect blood and tissue samples for analysis in research laboratories. By looking at the results of the laboratory findings and the clinical data together, we will start to answer the questions about why osteosarcomas arise and grow, what makes it spread, and why some patients respond to treatment better than others. As time goes on, we plan to use this information to develop clinical trials of new treatments.

Alongside this, we want to find out more about how osteosarcoma and its treatments affect the lives of those living with this disease. This information will help us to provide the most appropriate care and support that will meet the needs of each patient.

Ultimately, our aim is to improve the care and treatment of osteosarcoma patients so that they may live longer and better lives.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

25 Oct 2019 21 Mar 2025

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


• Osteosarcoma diagnosis more than three months prior to registration


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Beatson West Of Scotland Cancer Centre
    1053 Great Western Road
    Glasgow
    G12 0YN
  • Royal Hospital For Sick Children (glasgow)
    1345 Govan Road
    Glasgow
    G51 4TF
  • Royal Manchester Children's Hospital
    Oxford Road
    Manchester
    Greater Manchester
    M13 9WL
  • Grampian
    Summerfield House
    2 Eday Road
    Aberdeen
    AB15 6RE
  • The Christie
    550 Wilmslow Road
    withington
    Manchester
    Greater Manchester
    M20 4BX
  • Royal Aberdeen Children's Hospital
    Westburn Drive
    Aberdeen
    AB25 2ZG
  • Royal Hospital For Sick Children (edinburgh)
    9 Sciennes Road
    Edinburgh
    Lothian
    EH9 1LF
  • Noahs Ark Childrens Hospital For Wales
    Cardiff & Vale University Health Bd
    heath Park
    Cardiff
    South Glamorgan
    CF14 4XW

Sandra Strauss
s.strauss@ucl.ac.uk


ICONIC Trial Coordinator
ctc.iconic@ucl.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University College London and funded by Bone Cancer Research Trust .




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for Trial ID: CPMS 41346

Last updated 19 August 2025

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